Jefferson Airplane Takes Off is the debut album of San Francisco Rock band Jefferson Airplane, released in August 1966. The personnel differs from the later "classic" lineup and the music is more Folk-Rock than the harder psychedelic sound for which the band later became famous.

Signe Toly Anderson was the female vocalist and Skip Spence played drums. Both left the group shortly after the album's release and were replaced by Grace Slick and Spencer Dryden, respectively.